Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 4/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877889 | 0.86 | HTR3A (0.35) | HTR3ARETKDRPIK3CDPIK3CG | |
| SCHEMBL4777015 | 0.77 | ELANE (0.55) | HTR4ELANEKMT2A | |
| SCHEMBL8878245 | 0.77 | L3MBTL1 (0.40) | HTR3AHTR4MAPTHTTADORA2A | |
| Hydrochloric Acid SCHEMBL27569092 | 0.76 | ELANE (0.54) | HTR4ELANEKMT2A | |
| Oxalic Acid SCHEMBL7429472 | 0.73 | ELANE (0.55) | HTR4ELANEKMT2A | |
| Oxalic Acid SCHEMBL27529758 | 0.73 | ELANE (0.55) | HTR4ELANEKMT2A | |
| SCHEMBL2592776 | 0.73 | PARP1 (0.43) | KDRPIK3CDPIK3CGABL1EGFR | |
| SCHEMBL22791390 | 0.72 | KDM4E (0.35) | SMN1; SMN2AURKA | |
| SCHEMBL4610481 | 0.71 | HTR4 (0.38) | HTR4KMT2AGAA | |
| SCHEMBL8876380 | 0.71 | EGFR (0.40) | HTR3AHTR4EGFRADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |