Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876503 | 0.86 | HTR3A (0.38) | HTR3APIK3CDABL1EGFRHCK | |
| SCHEMBL8875819 | 0.80 | ELANE (0.50) | CFDELANESMN1; SMN2KMT2A | |
| SCHEMBL8877989 | 0.79 | L3MBTL1 (0.37) | HTR3AMAPTCFDELANEL3MBTL1 | |
| SCHEMBL20943695 | 0.74 | CNR1 (0.38) | CFDRET | |
| SCHEMBL8877233 | 0.74 | JAK2 (0.38) | HTR3APLA2G2AHCAR3MAPTHTT | |
| SCHEMBL8877375 | 0.74 | HCAR3 (0.40) | HTR3APLA2G2AHCAR3MAPTHTT | |
| SCHEMBL20589160 | 0.72 | ALDH1A1 (0.41) | MAPTSMN1; SMN2RETKMT2AMEN1 | |
| SCHEMBL8713436 | 0.72 | HTR3A (0.51) | HTR3A | |
| SCHEMBL8713439 | 0.72 | HTR3A (0.51) | HTR3A | |
| SCHEMBL8714873 | 0.70 | HTR3A (0.52) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |