SCHEMBL8883201

SCHEMBL8883201

O=P([O-])(O)Oc1cccc2ccccc12.[Na+]

nearest known ligand 0.53

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS1 known ✓ P23219 1/20 0.47
BTN3A1 O00481 2/20 0.52
GPR84 Q9NQS5 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 3/20 0.47
PGR P06401 1/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
KDM4E B2RXH2 2/20 0.45
HPGD P15428 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
OGG1 O15527 1/20 0.44
ACP3 P15309 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
RAB9A P51151 1/20 0.42
PTK2B Q14289 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370194 1.00 BTN3A1 (0.52) BTN3A1GPR84ALDH1A1HSD17B10PGR
Water SCHEMBL13736613 0.98 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR
Water SCHEMBL29475620 0.98 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR
SCHEMBL728493 0.87 BTN3A1 (0.52) BTN3A1GPR84ALDH1A1HSD17B10PGR
SCHEMBL29769247 0.87 BTN3A1 (0.52) BTN3A1GPR84ALDH1A1HSD17B10PGR
SCHEMBL8657077 0.85 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR
SCHEMBL9318274 0.85 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR
Silver SCHEMBL11322824 0.85 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR
SCHEMBL2963442 0.85 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR
SCHEMBL11322830 0.85 BTN3A1 (0.51) BTN3A1GPR84ALDH1A1HSD17B10PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11428444-B2 Electrocaloric heat transfer system CARRIER CORPORATION (US) 2022-08-30 US claimed
CN-108299783-B High-strength flame-retardant cable material and preparation method thereof 湖南辰砾新材料有限公司 2020-05-19 CN claimed
CN-111171500-A Preparation method of high-strength flame-retardant cable material 湖南辰砾新材料有限公司 2020-05-19 CN claimed
US-5665802-A REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-09-09 US claimed
CN-118076694-A PVDF film with high electromechanical efficiency and gel casting method for forming the film 元平台技术有限公司 2024-05-24 CN disclosed
US-11683987-B2 Electrocaloric heat transfer system comprising copolymers CARRIER CORPORATION (US) 2023-06-20 US disclosed
WO-2023064206-A1 PVDF THIN FILMS HAVING HIGH ELECTROMECHANICAL EFFICIENCY AND A GEL CASTING METHOD FOR FORMING SAME META PLATFORMS TECHNOLOGIES, LLC (US) 2023-04-20 WO disclosed
US-20230116775-A1 PVDF THIN FILMS HAVING HIGH ELECTROMECHANICAL EFFICIENCY AND A GEL CASTING METHOD FOR FORMING SAME FACEBOOK TECHNOLOGIES, LLC 2023-04-13 US disclosed
US-11428444-B2 Electrocaloric heat transfer system CARRIER CORPORATION (US) 2022-08-30 US disclosed
US-20210151655-A1 ELECTROCALORIC HEAT TRANSFER SYSTEM COMPRISING COPOLYMERS CARRIER CORPORATION 2021-05-20 US disclosed
US-20210061829-A1 Composition, Film, Laminate Structure, Light-Emitting Device, and Display SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-04 US disclosed
EP-3747973-A1 COMPOSITION, FILM, LAMINATE STRUCTURE, LIGHT-EMITTING DEVICE, AND DISPLAY SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2020-12-09 EP disclosed
EP-3475382-A1 ELECTROCALORIC HEAT TRANSFER SYSTEM United Technologies Corporation (US) 2019-05-01 EP disclosed
WO-2018004520-A1 ELECTROCALORIC HEAT TRANSFER SYSTEM UNITED TECHNOLOGIES CORPORATION (US) 2018-01-04 WO disclosed
EP-2726553-A2 A MELT PROCESSABLE COMPOSITION AND METHOD OF MAKING Saint-gobain Performance Plastics Corporation (US) 2014-05-07 EP disclosed
US-20130005878-A1 MELT PROCESSABLE COMPOSITION AND METHOD OF MAKING UNIVERSITY OF MASSACHUSETTS (US) 2013-01-03 US disclosed
WO-2013003758-A2 A MELT PROCESSABLE COMPOSITION AND METHOD OF MAKING SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2013-01-03 WO disclosed
US-5665802-A REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-09-09 US disclosed
EP-0350958-B1 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI CHEMICAL IND (JP) 1994-12-21 EP disclosed
EP-0350958-A2 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061829-A1 Composition, Film, Laminate Structure, Light-Emitting Device, and Display TMEM109, ITGB1, ANO1 PTGS1 4564/4885BTN3A1 511/4885GPR84 3318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.