Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 7/20 | 0.45 |
| ▸ | CA2 known ✓ | P00918 | 7/20 | 0.45 |
| ▸ | CA12 known ✓ | O43570 | 6/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.52 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.52 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.52 |
| ▸ | IGF2R | P11717 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542344 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521297 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521065 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521070 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521142 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521051 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL7114633 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521293 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521049 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR | |
| SCHEMBL1521141 | 0.89 | L3MBTL1 (0.45) | IGF2RMEN1KMT2ATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514588-B1 | Novel phosphobetaine and detergent and cosmetic containing the same | KAO CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5409705-A | Phosphobetaine and detergent and cosmetic containing the same | KAO CORPORATION (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0514588-A2 | Novel phosphobetaine and detergent and cosmetic containing the same | Kao Corporation (JP) | 1991-11-25 | — | — | EP | disclosed |