Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.55 |
| ▸ | NPC1L1 | Q9UHC9 | 7/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893501 | 0.89 | BDKRB2 (0.53) | BDKRB2NPC1L1CCR5OPRK1OPRM1 | |
| SCHEMBL8894056 | 0.83 | BDKRB2 (0.59) | BDKRB2NPC1L1 | |
| SCHEMBL1855447 | 0.79 | NPC1L1 (0.70) | BDKRB2NPC1L1OPRK1OPRM1DDR1 | |
| SCHEMBL8894874 | 0.78 | BDKRB2 (0.57) | BDKRB2NPC1L1DDR1 | |
| SCHEMBL8897218 | 0.78 | NPC1L1 (0.60) | BDKRB2NPC1L1OPRK1OPRM1DDR1 | |
| SCHEMBL8894157 | 0.76 | NPC1L1 (0.59) | BDKRB2NPC1L1OPRK1OPRM1DDR1 | |
| SCHEMBL8893424 | 0.75 | CCR5 (0.51) | NPC1L1CCR5OPRK1OPRM1OPRD1 | |
| SCHEMBL4130653 | 0.74 | CCR5 (0.39) | NPC1L1CCR5USP30USP2SMN1; SMN2 | |
| SCHEMBL8910702 | 0.73 | BDKRB2 (0.52) | BDKRB2NPC1L1OPRK1OPRM1OPRD1 | |
| SCHEMBL5134060 | 0.71 | GRIN2B (0.49) | BDKRB2NPC1L1CCR5DDR1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610142-A | Bradykinin antagonist pseudopeptide derivatives of substituted 4-keto-1,3,8-triazaspiro[4.5]decan-3-alkanoic acids | SCIOS INC. (US) | 1997-03-11 | — | — | US | disclosed |