Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 4/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898180 | 0.86 | SMN1; SMN2 (0.43) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL8896841 | 0.73 | ALDH1A1 (0.40) | CTSSKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8549086 | 0.71 | CTSS (0.64) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL8549092 | 0.71 | CTSS (0.64) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL8961019 | 0.71 | ACE (0.60) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL8961015 | 0.71 | ACE (0.60) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL8895941 | 0.71 | CTSB (0.56) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL9006092 | 0.70 | CA2 (0.74) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL9006099 | 0.70 | CA2 (0.74) | CTSSCTSLCTSBKMT2AMEN1 | |
| SCHEMBL9754245 | 0.70 | CTSD (0.62) | CTSSCTSLCTSBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |