Pyromellitic Acid

Pyromellitic Acid

SCHEMBL890384

C=C(C)C(=O)O.C=C(C)C(=O)O.O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 1/20 0.38
CYP1A2 P05177 1/20 0.38
CSNK2A1 P68400 1/20 0.37
CFD P00746 1/20 0.36
NOTUM Q6P988 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA7 P43166 4/20 0.35
CA9 Q16790 4/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
CA4 P22748 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LCK P06239 1/20 0.35
CA14 Q9ULX7 2/20 0.34
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyromellitic Acid SCHEMBL28948501 0.97 ALDH1A1 (0.36) ALDH1A1ALOX15CYP1A2CSNK2A1CFD
Pyromellitic Acid SCHEMBL22418772 0.84 TGFBR1 (0.34) ALDH1A1CFDTDP1MEN1KMT2A
Pyromellitic Acid SCHEMBL10889309 0.83 LCK (0.47) ALDH1A1ALOX15CYP1A2CSNK2A1CFD
Phthalic Acid SCHEMBL30894712 0.80 ALDH1A1 (0.67) ALDH1A1ALOX15SMN1; SMN2CA12CA1
Phthalic Acid SCHEMBL1302034 0.80 ALDH1A1 (0.67) ALDH1A1ALOX15SMN1; SMN2CA12CA1
Phthalic Acid SCHEMBL36441 0.80 ALDH1A1 (0.67) ALDH1A1ALOX15SMN1; SMN2CA12CA1
Phthalic Acid SCHEMBL30894713 0.80 ALDH1A1 (0.67) ALDH1A1ALOX15SMN1; SMN2CA12CA1
Pyromellitic Acid SCHEMBL5323041 0.80 ALDH1A1 (0.47) ALDH1A1ALOX15CYP1A2SMN1; SMN2CA12
Pyromellitic Acid SCHEMBL27686459 0.80 ALDH1A1 (0.47) ALDH1A1ALOX15CYP1A2SMN1; SMN2CA12
Pyromellitic Acid SCHEMBL22443 0.80 ALDH1A1 (0.53) ALDH1A1ALOX15CYP1A2SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782599-B1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2025-09-17 EP claimed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2021-02-25 US claimed
US-7226960-B2 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2007-06-05 US claimed
US-20030207960-A1 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-06 US claimed
US-20250382506-A1 SHELF STABLE ADHESIVE COMPOSITIONS UNIV KANSAS (US) 2025-12-18 US disclosed
US-20250340760-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES UNIV KANSAS (US) 2025-11-06 US disclosed
US-12351745-B2 Single-component adhesive compositions OHIO STATE INNOVATION FOUNDATION (US) 2025-07-08 US disclosed
EP-4547770-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES University of Kansas (US) 2025-05-07 EP disclosed
EP-4547771-A1 SHELF STABLE ADHESIVE COMPOSITIONS University of Kansas (US) 2025-05-07 EP disclosed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US disclosed
US-20240158253-A1 Optically Stable Transparent Zinc Oxide for Dental Applications DEN-MAT HOLDINGS, LLC (US) 2024-05-16 US disclosed
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT VOCO GMBH (DE) 2012-05-10 US disclosed
US-20120082959-A1 Polymerizable Compounds Comprising a Polyalicylic Structure Element VOCO GMBH (DE) 2012-04-05 US disclosed
US-20120082954-A1 Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal VOCO GMBH (DE) 2012-04-05 US disclosed
US-7226960-B2 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2007-06-05 US disclosed
US-20030207960-A1 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-06 US disclosed
US-5753765-A BLOCK POLYMERS FOR DENTAL AND/OR MEDICAL PURPOSES ERNST MUHLBAUER KG (DE) 1998-05-19 US disclosed
US-5601805-A APPLYING DILUTE AQUEOUS SOLUTION OF HYDROXY- OR AMINO-CARBOXYLIC ACID TO TOOTH SURFACE BEFORE BONDING IT TO POLYMERIC MATERIAL M G DENT, LLC 1997-02-11 US disclosed
US-5362769-A Light curable; high molecular weight resin, hydrophilic monomer, photoinintiator, reducing agent, leachable fluoride leachable fluoride, acyl peroxide, fillers; wettability, toughness ORMCO CORPORATION (US) 1994-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 ALDH1A1 1481/4885ALOX15 1849/4885CYP1A2 2949/4885
US-20120082959-A1 Polymerizable Compounds Comprising a Polyalicylic Structure Element PCBP1, PUF60, PARG ALDH1A1 3882/4885ALOX15 2639/4885CYP1A2 4416/4885
US-20250340760-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES FN1, EPCAM, VCL ALDH1A1 1615/4885ALOX15 1525/4885CYP1A2 4794/4885
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES NCAPH, RCC1, NCAPD2 ALDH1A1 1481/4885ALOX15 1849/4885CYP1A2 2949/4885
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT CAD, PCBP1, PPIP5K2 ALDH1A1 2866/4885ALOX15 902/4885CYP1A2 4807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.