Morpholine

Morpholine

SCHEMBL890524

C1COCCN1.Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Morpholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 1/20 0.42
USP2 O75604 1/20 0.42
ADRB1 P08588 1/20 0.42
GAA P10253 2/20 0.41
NPC1 O15118 1/20 0.41
SNCA P37840 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL6562102 0.92 L3MBTL1 (0.39) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Oxazolidine SCHEMBL10370071 0.90 LMNA (0.41) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Aziridine SCHEMBL5185484 0.89 ALDH1A1 (0.50) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Dioxane SCHEMBL11309706 0.87 L3MBTL1 (0.49) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Piperazine SCHEMBL5875357 0.87 ALDH1A1 (0.49) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Dioxane SCHEMBL5177507 0.87 L3MBTL1 (0.49) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Piperazine SCHEMBL7635861 0.87 ALDH1A1 (0.49) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Oxirane SCHEMBL10380952 0.85 ALDH1A1 (0.50) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Pyrrolidine SCHEMBL2531422 0.84 ALDH1A1 (0.46) L3MBTL1ALDH1A1LMNAMAPTKDM4E
Tetrahydrofuran SCHEMBL2775004 0.84 ALDH1A1 (0.48) L3MBTL1ALDH1A1LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118256180-A Preparation method of glyoxal-melamine-formaldehyde copolycondensation impregnating resin adhesive 德华兔宝宝装饰新材股份有限公司 2024-06-28 CN claimed
EP-3455280-B9 IMPREGNATING RESIN COMPOSITION, RESIN COATING, LAMINATE CONTAINING SAME, IMPREGNATION PRODUCT, AND METHOD FOR PRODUCING SAME FRITZ EGGER GMBH & CO OG (AT) 2023-01-18 EP claimed
EP-3691847-B1 RESIN COMPOSITION, RESIN COATING, LAMINATES AND IMPREGNATION PRODUCTS CONTAINING SAME, AND METHOD FOR PRODUCING SAME FRITZ EGGER GMBH & CO OG (AT) 2021-12-29 EP claimed
US-10995209-B2 Impregnating resin composition, resin coating, laminate containing same, impregnation product, and method for producing same FRITZ EGGER GMBH & CO. OG (AT) 2021-05-04 US claimed
CN-109942721-B Aqueous solution of hydroxymethyl urea modified cationic polysaccharide 淮海工学院 2021-04-02 CN claimed
CN-109735199-B Single-component water-based silicon steel sheet paint 山东省环科院环境检测有限公司 2021-03-09 CN claimed
EP-3691847-A1 RESIN COMPOSITION, RESIN COATING, LAMINATES AND IMPREGNATION PRODUCTS CONTAINING SAME, AND METHOD FOR PRODUCING SAME Fritz Egger GmbH & Co. OG (AT) 2020-08-12 EP claimed
US-20190256702-A1 Impregnating Resin Composition, Resin Coating, Laminate Containing Same, Impregnation Product, and Method for Producing Same FRITZ EGGER GMBH & CO. OG (AT) 2019-08-22 US claimed
CN-109912290-A A kind of waterproof magnesium substrate and its production method 浙江晶通塑胶有限公司 2019-06-21 CN claimed
CN-109735199-A A kind of single-component water-based lamination coating 苏日艳 2019-05-10 CN claimed
CN-107011631-B One kind heat filling containing crystalline flake graphite and the preparation method and application thereof 杭州本松新材料技术股份有限公司 2019-04-05 CN claimed
EP-3455280-A1 IMPREGNATING RESIN COMPOSITION, RESIN COATING, LAMINATE CONTAINING SAME, IMPREGNATION PRODUCT, AND METHOD FOR PRODUCING SAME Fritz Egger GmbH & Co. OG (AT) 2019-03-20 EP claimed
WO-2017194397-A1 IMPREGNATING RESIN COMPOSITION, RESIN COATING, LAMINATE CONTAINING SAME, IMPREGNATION PRODUCT, AND METHOD FOR PRODUCING SAME FRITZ EGGER GMBH & CO. OG (AT) 2017-11-16 WO claimed
CN-107011631-A A kind of heat filling containing crystalline flake graphite and preparation method and application 杭州本松新材料技术股份有限公司 2017-08-04 CN claimed
EP-0252875-B1 MICROBICIDAL AGENT CIBA-GEIGY AG (CH) 1993-01-27 EP claimed
JP-11228868-A None JP disclosed
CN-122095297-A Composition for forming cured film, alignment material, and phase difference material 2026-05-26 CN disclosed
US-4038225-A ALKYD RESIN, MELAMINE RESIN, ORGANOSULFONIC ACID, SOLVENT KANSAI PAINT COMPANY, LTD. (JA) 1977-07-26 US disclosed
US-4008293-A ACRYLIC COPOLYMER, AMINOPLAST, BINDER PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-4002781-A Process for making carrier sheets containing hardenable polyester resins TH. GOLDSCHMIDT AG (DT) 1977-01-11 US disclosed