Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 14/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905430 | 0.87 | FCER2 (0.56) | SLC6A2SLC6A4SLC6A3FCER2MMP2 | |
| SCHEMBL8235027 | 0.81 | MMP9 (0.43) | SLC6A2SLC6A4SLC6A3FCER2MMP9 | |
| SCHEMBL8914696 | 0.81 | FCER2 (0.50) | FCER2MMP2MMP9MMP8 | |
| SCHEMBL8906164 | 0.79 | CYP1A2 (0.49) | — | |
| SCHEMBL6316406 | 0.76 | CTSS (0.48) | HTRA1CTSLCTSBCTSS | |
| SCHEMBL7132131 | 0.74 | MMP2 (0.54) | FCER2MMP2MMP9MMP8 | |
| SCHEMBL7771306 | 0.73 | CA2 (0.45) | — | |
| SCHEMBL6316677 | 0.71 | GHSR (0.45) | FCER2MMP9MMP8CTSLCTSB | |
| SCHEMBL6850527 | 0.69 | CYP3A4 (0.46) | SLC6A2SLC6A4SLC6A3MMP9MMP8 | |
| SCHEMBL7165087 | 0.68 | MMP9 (0.42) | SLC6A2SLC6A4SLC6A3FCER2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |