Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 10/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910700 | 0.88 | REN (0.40) | P2RX1F2RRENAKR1C3MDM2 | |
| SCHEMBL8909367 | 0.84 | P2RX1 (0.42) | P2RX1F2RRENAKR1C3MDM2 | |
| SCHEMBL8908848 | 0.83 | F2R (0.37) | P2RX1F2RRENAKR1C3MDM2 | |
| SCHEMBL8909154 | 0.79 | REN (0.41) | P2RX1F2RREN | |
| SCHEMBL8909458 | 0.78 | PYGL (0.36) | P2RX1RENAKR1C3 | |
| SCHEMBL8910563 | 0.78 | REN (0.41) | P2RX1REN | |
| SCHEMBL8910252 | 0.77 | KDM4E (0.39) | RENAKR1C3 | |
| SCHEMBL8910552 | 0.76 | REN (0.36) | P2RX1F2RREN | |
| SCHEMBL8910197 | 0.76 | REN (0.36) | P2RX1F2RREN | |
| SCHEMBL8909424 | 0.76 | SIRT2 (0.34) | P2RX1RENAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |