Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | PGC | P20142 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910205 | 0.76 | GPR132 (0.36) | REN | |
| SCHEMBL8908817 | 0.74 | REN (0.38) | REN | |
| SCHEMBL8910700 | 0.72 | REN (0.40) | REN | |
| SCHEMBL9523860 | 0.70 | REN (0.46) | RENPGC | |
| SCHEMBL8909458 | 0.69 | PYGL (0.36) | REN | |
| SCHEMBL8910252 | 0.69 | KDM4E (0.39) | REN | |
| SCHEMBL7274989 | 0.69 | P2RX1 (0.31) | — | |
| SCHEMBL8909154 | 0.68 | REN (0.41) | REN | |
| SCHEMBL22263507 | 0.68 | REN (0.53) | REN | |
| SCHEMBL8910563 | 0.68 | REN (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |