Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MELK | Q14680 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913335 | 0.91 | KCNA5 (0.47) | SLC1A3SLC1A2SLC1A1MMP1ADAM17 | |
| SCHEMBL8913898 | 0.85 | KCNA5 (0.47) | KCNA5ADAMTS4MMP2MELKMAPK1 | |
| SCHEMBL8912385 | 0.81 | KDM4E (0.48) | SLC1A3SLC1A2SLC1A1MMP1KCNA5 | |
| SCHEMBL8914187 | 0.78 | ADAMTS4 (0.66) | MMP1ADAMTS4MMP2MMP3MMP13 | |
| SCHEMBL8913812 | 0.78 | ROCK2 (0.51) | SLC1A3SLC1A2SLC1A1MMP1ADAM17 | |
| SCHEMBL8913118 | 0.74 | MMP2 (0.67) | SLC1A3SLC1A2SLC1A1MMP1ADAMTS4 | |
| SCHEMBL9541267 | 0.72 | PRKD3 (0.61) | MMP1ADAM17KCNA5KDM4EMELK | |
| SCHEMBL8915915 | 0.71 | ROCK2 (0.45) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8914671 | 0.71 | ROCK2 (0.45) | KDM4EALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL8914320 | 0.71 | BCAT2 (0.45) | SLC1A3SLC1A2SLC1A1ADAMTS4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663174-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF KINASES, ANTIARTHRITIC AGENTS | PHARNO-WEDROPHARM GMBH (DE) | 1997-09-02 | — | — | US | disclosed |
| EP-0602028-B1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO WEDROPHARM GMBH (DE) | 1996-01-17 | — | — | EP | disclosed |