Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912497 | 1.00 | TSHR (0.35) | TSHRALDH1A1KDM4EGMNNPPM1B | |
| SCHEMBL8912493 | 1.00 | TSHR (0.35) | TSHRALDH1A1KDM4EGMNNPPM1B | |
| SCHEMBL9152795 | 1.00 | TSHR (0.35) | TSHRALDH1A1KDM4EGMNNPPM1B | |
| SCHEMBL13103999 | 0.85 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL24062348 | 0.81 | OPRM1 (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8844934 | 0.74 | SIGMAR1 (0.34) | — | |
| SCHEMBL23253720 | 0.74 | SIGMAR1 (0.34) | — | |
| SCHEMBL9846838 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL9846845 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL9846852 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262033-B1 | ETHYLENEDIAMINETETRAACETIC ACID BIS(AMIDE) DERIVATIVES AND THEIR RESPECTIVE COMPLEXES WITH MN(II) ION FOR USE AS MRI CONTRAST AGENT | BRACCO IMAGING SPA (IT) | 2020-08-26 | — | — | EP | disclosed |
| US-10265422-B2 | Ethylenediaminetetraacetic acid bis(amide) derivatives and their respective complexes with Mn(II) ion for use as MRI contrast agent | BRACCO IMAGING S.P.A. (IT) | 2019-04-23 | — | — | US | disclosed |
| US-20180036436-A1 | ETHYLENEDIAMINETETRAACETIC ACID BIS(AMIDE) DERIVATIVES AND THEIR RESPECTIVE COMPLEXES WITH MN(II) ION FOR USE AS MRI CONTRAST AGENT | BRACCO IMAGING S.P.A. (IT) | 2018-02-08 | — | — | US | disclosed |
| US-20180036436-A1 | ETHYLENEDIAMINETETRAACETIC ACID BIS(AMIDE) DERIVATIVES AND THEIR RESPECTIVE COMPLEXES WITH MN(II) ION FOR USE AS MRI CONTRAST AGENT | BRACCO IMAGING S.P.A. (IT) | 2018-02-08 | — | — | US | disclosed |
| WO-2016135523-A1 | NEW SUBSTITUTED ETHYLENE-DIAMINE-TETRAACETIC-ACID-BIS(AMIDE) DERIVATIVES AND USE THEREOF AS LIGAND CONTAINING MN (II) OF MRI CONTRAST AGENT | DEBRECENI EGYETEM (HU) | 2016-09-01 | — | — | WO | disclosed |
| WO-2016135234-A1 | ETHYLENEDIAMINETETRAACETIC ACID BIS(AMIDE) DERIVATIVES AND THEIR RESPECTIVE COMPLEXES WITH MN(II) ION FOR USE AS MRI CONTRAST AGENT | DEBRECENI EGYETEM (HU) | 2016-09-01 | — | — | WO | disclosed |
| US-5693310-A | Amide complexes | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036436-A1 | ETHYLENEDIAMINETETRAACETIC ACID BIS(AMIDE) DERIVATIVES AND THEIR RESPECTIVE COMPLEXES WITH MN(II) ION FOR USE AS MRI CONTRAST AGENT | NAAA, FHIT, NBAS | TSHR 3561/4885ALDH1A1 4713/4885KDM4E 2783/4885 |
| US-10265422-B2 | Ethylenediaminetetraacetic acid bis(amide) derivatives and their respective complexes with Mn(II) ion for use as MRI contrast agent | NAAA, FHIT, NBAS | TSHR 3561/4885ALDH1A1 4713/4885KDM4E 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.