Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | BRD1 | O95696 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917334 | 0.80 | MEN1 (0.42) | SLC40A1NPSR1ALDH1A1HTTLMNA | |
| SCHEMBL8916155 | 0.78 | HTR6 (0.36) | SLC40A1TSHRALDH1A1HTTHSD17B10 | |
| SCHEMBL8918668 | 0.72 | CA12 (0.46) | HTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL9231677 | 0.71 | CA1 (0.58) | HTR2AHTR2C | |
| SCHEMBL8691901 | 0.70 | PTGS2 (0.46) | TSHRALDH1A1HTTHSD17B10LMNA | |
| SCHEMBL8917188 | 0.68 | PLAU (0.48) | TSHRNPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL8639257 | 0.66 | ADRA2A (0.42) | SLC40A1TSHRALDH1A1HTTHSD17B10 | |
| SCHEMBL8693823 | 0.66 | PTGS2 (0.41) | ALDH1A1HTTHSD17B10POLBMAPT | |
| SCHEMBL8692197 | 0.66 | HTT (0.50) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL8917762 | 0.66 | KAT6A (0.38) | SLC40A1ALDH1A1HTTPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |