Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917277 | 0.91 | TRPV4 (0.34) | FBP1TRPV4ALDH1A1ACLYHSD17B10 | |
| SCHEMBL8916660 | 0.89 | SGK1 (0.33) | LMNASGK1 | |
| SCHEMBL8917485 | 0.84 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1LMNAGLAHSD11B1 | |
| SCHEMBL8921166 | 0.82 | CA2 (0.33) | FBP1MEN1KMT2A | |
| SCHEMBL8917798 | 0.75 | MCL1 (0.47) | FBP1L3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL8918579 | 0.74 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1LMNAGLAHSD11B1 | |
| SCHEMBL8691401 | 0.73 | — | — | |
| SCHEMBL8916165 | 0.73 | LMNA (0.40) | FBP1L3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL8916678 | 0.73 | SGK1 (0.38) | L3MBTL1ALDH1A1LMNAGLASGK1 | |
| SCHEMBL8916271 | 0.69 | CA1 (0.43) | L3MBTL1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |