Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 3/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916660 | 0.91 | SGK1 (0.33) | MAPTSGK1 | |
| SCHEMBL8917778 | 0.83 | SGK1 (0.39) | SGK1 | |
| SCHEMBL8918537 | 0.80 | FBP1 (0.33) | POLBSGK1 | |
| SCHEMBL8916678 | 0.74 | SGK1 (0.38) | MAPTSMN1; SMN2SGK1 | |
| SCHEMBL8917459 | 0.73 | MCL1 (0.41) | — | |
| SCHEMBL8921166 | 0.73 | CA2 (0.33) | — | |
| SCHEMBL8917282 | 0.71 | PLAU (0.38) | SGK1 | |
| SCHEMBL8691401 | 0.65 | — | — | |
| SCHEMBL8918176 | 0.65 | CCR3 (0.36) | — | |
| SCHEMBL8917334 | 0.61 | MEN1 (0.42) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |