Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919081 | 0.86 | PDE1B (0.41) | ALDH1A1KDM4EHTR1AGAAHSD17B10 | |
| SCHEMBL8918497 | 0.85 | DRD4 (0.53) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL8917938 | 0.84 | PDE1B (0.43) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8918424 | 0.76 | HTR1A (0.51) | DRD2DRD3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL8920545 | 0.74 | SIGMAR1 (0.52) | DRD2DRD3HTR1AADRA1ADRD4 | |
| SCHEMBL8918611 | 0.74 | SIGMAR1 (0.41) | ALDH1A1HTR1AUSP2SLC6A2SLC6A4 | |
| SCHEMBL8918622 | 0.73 | HRH3 (0.41) | HTR1ACYP1A2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8918838 | 0.73 | DRD4 (0.51) | KMT2ADRD2DRD3HTR1ADRD4 | |
| SCHEMBL8917996 | 0.72 | SIGMAR1 (0.44) | KMT2AALDH1A1HTR1AHSD17B10 | |
| SCHEMBL8624806 | 0.72 | HSD17B10 (0.35) | MEN1KMT2AALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |