Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919620 | 0.91 | MAPT (0.34) | SGK1MAPT | |
| SCHEMBL8918537 | 0.89 | FBP1 (0.33) | SGK1LMNA | |
| SCHEMBL8916678 | 0.84 | SGK1 (0.38) | SGK1LMNATP53MAPT | |
| SCHEMBL8921166 | 0.82 | CA2 (0.33) | — | |
| SCHEMBL8917277 | 0.82 | TRPV4 (0.34) | MAPT | |
| SCHEMBL8917778 | 0.74 | SGK1 (0.39) | SGK1 | |
| SCHEMBL8691401 | 0.74 | — | — | |
| SCHEMBL8917485 | 0.73 | ALDH1A1 (0.49) | LMNA | |
| SCHEMBL8916271 | 0.70 | CA1 (0.43) | — | |
| SCHEMBL8689042 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |