Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917201 | 0.86 | ELANE (0.32) | OPRD1CCR1ELANE | |
| SCHEMBL8916271 | 0.83 | CA1 (0.43) | CA2KMT2AMEN1SLC40A1HSD17B2 | |
| SCHEMBL8916660 | 0.82 | SGK1 (0.33) | — | |
| SCHEMBL8918537 | 0.82 | FBP1 (0.33) | KMT2AMEN1FBP1 | |
| SCHEMBL8691401 | 0.75 | — | — | |
| SCHEMBL8919620 | 0.73 | MAPT (0.34) | — | |
| SCHEMBL8919219 | 0.72 | CA1 (0.45) | CA2KMT2AMEN1SLC40A1HSD17B2 | |
| SCHEMBL8917277 | 0.72 | TRPV4 (0.34) | FBP1 | |
| SCHEMBL8917188 | 0.72 | PLAU (0.48) | CA2KDM4ESCN9A | |
| SCHEMBL8917334 | 0.72 | MEN1 (0.42) | KDM4EKMT2AMEN1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |