SCHEMBL892213

SCHEMBL892213

C=C(C)C(=O)NCC(C)(C)C=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763131 0.90 ALDH1A1 (0.38) ALDH1A1
SCHEMBL3232710 0.79 TGFBR1 (0.36) TGFBR1KDM4EALDH1A1
SCHEMBL13862890 0.79 SMN1; SMN2 (0.45) TGFBR1KDM4EALDH1A1
SCHEMBL9135839 0.78 KDM4E (0.33) KDM4E
SCHEMBL321577 0.77 TGFBR1 (0.35) TGFBR1KDM4EALDH1A1
SCHEMBL2426544 0.76 L3MBTL1 (0.31) ALDH1A1
SCHEMBL28842148 0.75 TGFBR1 (0.34) TGFBR1ALDH1A1
SCHEMBL819336 0.75 TDP1 (0.35) TGFBR1ALDH1A1
SCHEMBL6240859 0.74 TGFBR1 (0.36) TGFBR1KDM4EALDH1A1
SCHEMBL4203690 0.74 CYP2D6 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196084-A1 AQUEOUS CROSSLINKABLE VINYL GRAFT COPOLYMER COMPOSITIONS DSM IP ASSETS B.V. (NL) 2011-08-11 US claimed
EP-2032648-A1 AQUEOUS CROSSLINKABLE VINYL GRAFT COPOLYMER COMPOSITIONS DSMIP Assets B.V. (NL) 2009-03-11 EP claimed
WO-2007147561-A1 AQUEOUS CROSSLINKABLE VINYL GRAFT COPOLYMER COMPOSITIONS DSM IP ASSETS B.V. (NL) 2007-12-27 WO claimed
EP-3935113-B1 AQUEOUS COATING COMPOSITION ALLNEX NETHERLANDS BV (NL) 2026-05-06 EP disclosed
EP-4720204-A2 WATER-BASED COATING COMPOSITIONS FOR SCUFF AND SCRATCH RESISTANCE Swimc LLC (US) 2026-04-08 EP disclosed
EP-4720198-A2 SCUFF AND MAR RESISTANT COATING COMPOSITIONS Swimc LLC (US) 2026-04-08 EP disclosed
US-12595384-B1 Polymer latex for matte films SWIMC LLC (US) 2026-04-07 US disclosed
US-12565542-B2 Waterborne coating composition ALLNEX NETHERLANDS BV (NL) 2026-03-03 US disclosed
US-20260035578-A1 SCUFF AND MAR RESISTANT COATING COMPOSITIONS SWIMC LLC (US) 2026-02-05 US disclosed
US-12534634-B2 Aqueous coating composition ALLNEX NETHERLANDS (NL) 2026-01-27 US disclosed
US-20250354015-A1 COMPOSITE PARTICLES FOR WATER-BASED COATING COMPOSITIONS SWIMC LLC (US) 2025-11-20 US disclosed
WO-2000056826-A1 CROSSLINKABLE COATING COMPOSITIONS AVECIA B.V. (NL) 2000-09-28 WO disclosed
WO-2000056827-A1 CROSSLINKABLE COATING COMPOSITIONS AVECIA BV (NL) 2000-09-28 WO disclosed
WO-2000024837-A1 AQUEOUS COATING COMPOSITION COMPRISING A MIXTURE OF POLYURETHANE DISPERSIONS AKZO NOBEL N.V. (NL) 2000-05-04 WO disclosed
EP-0341886-B1 Aqueous coating compositions ZENECA RESINS BV (NL) 1994-12-07 EP disclosed
EP-0332326-B1 POLYURETHANE COATING COMPOSITIONS ICI RESINS BV (NL) 1993-03-03 EP disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0341886-A2 Aqueous coating compositions ZENECA RESINS BV (NL) 1989-11-15 EP disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595384-B1 Polymer latex for matte films TERT, MYD88, MACF1 TGFBR1 1462/4885KDM4E 1555/4885ALDH1A1 1501/4885
US-20260035578-A1 SCUFF AND MAR RESISTANT COATING COMPOSITIONS SMC4, SPATS2L, MEF2D TGFBR1 1978/4885KDM4E 324/4885ALDH1A1 284/4885
US-12565542-B2 Waterborne coating composition CHRM1, CHRM2, CCNT1 TGFBR1 875/4885KDM4E 3501/4885ALDH1A1 920/4885
US-12534634-B2 Aqueous coating composition CHRM1, CD274, CHRM2 TGFBR1 548/4885KDM4E 4198/4885ALDH1A1 839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.