SCHEMBL8924466

SCHEMBL8924466

CCOc1c(C)c(C)c(O)c(CNCCOc2cc(C)ccc2C(C)C)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 2/20 0.44
ALDH1A1 P00352 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPBWR1 P48145 1/20 0.43
MCHR1 Q99705 1/20 0.43
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 2/20 0.41
GAA P10253 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8924613 0.83 HTR1A (0.46) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL30298322 0.76 MEN1 (0.54) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL8923685 0.71 MEN1 (0.56) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL8924282 0.70 ADRA1D (0.58) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL8924045 0.70 ADRA1D (0.67) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL8960589 0.70 ALDH1A1 (0.55) MEN1KMT2ANPC1RAB9ANPSR1
SCHEMBL8246277 0.70 ALDH1A1 (0.55) MEN1KMT2AALDH1A1SMN1; SMN2TDP1
SCHEMBL9678575 0.70 L3MBTL4 (0.57) MEN1KMT2ANPC1RAB9ANPSR1
Hydrochloric Acid SCHEMBL8924776 0.69 ADRA1D (0.66) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL15086403 0.69 ALDH1A1 (0.62) MEN1KMT2ANPC1RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624961-A Benzylaminoethoxybenzene derivatives, production thereof and use thereof JAPAN TOBACCO INC. (JP) 1997-04-29 US disclosed
EP-0693474-A1 NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Toyo Boseki Kabushiki Kaisha (JP) 1996-01-24 EP disclosed