Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931862 | 0.86 | FFAR4 (0.47) | FFAR4GLO1S1PR1 | |
| SCHEMBL8931861 | 0.84 | FFAR4 (0.52) | FFAR4TERTGLO1CDK4CCND1 | |
| SCHEMBL8931909 | 0.75 | MAPT (0.41) | PPARG | |
| SCHEMBL10593438 | 0.73 | KMO (0.62) | ALOX5EPHX2ACLYPLGPLAU | |
| SCHEMBL19783673 | 0.72 | CDK4 (0.72) | TERTCDK4CCND1 | |
| SCHEMBL30582936 | 0.72 | CDK4 (0.72) | TERTCDK4CCND1 | |
| SCHEMBL7017402 | 0.71 | AGTR1 (0.44) | PPARG | |
| SCHEMBL27587769 | 0.71 | ALOX5 (0.50) | FFAR4ALOX5EPHX2CDK4CCND1 | |
| SCHEMBL1269116 | 0.71 | CDK4 (0.71) | TERTCDK4CCND1 | |
| SCHEMBL5487411 | 0.70 | P2RX7 (0.54) | FFAR4TERTALOX5EPHX2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |