Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20710739 | 0.80 | LTA4H (0.49) | DRD2DRD3LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8939016 | 0.80 | DRD2 (0.36) | DRD2DRD4DRD3LMNASMN1; SMN2 | |
| SCHEMBL4457781 | 0.77 | LMNA (0.39) | LMNASMN1; SMN2ALDH1A1LTA4HKMT2A | |
| SCHEMBL8939051 | 0.75 | LTA4H (0.39) | LMNALTA4HTSHRCHRNB2CHRNB4 | |
| SCHEMBL28876309 | 0.75 | LMNA (0.42) | DRD2DRD4DRD3LMNASMN1; SMN2 | |
| SCHEMBL30437039 | 0.75 | ACHE (0.35) | DRD2DRD4DRD3LMNASMN1; SMN2 | |
| SCHEMBL15417421 | 0.75 | CA2 (0.36) | ALDH1A1LTA4HKMT2ARAB9ATSHR | |
| SCHEMBL1724774 | 0.73 | LTA4H (0.42) | DRD2DRD3LMNAALDH1A1LTA4H | |
| SCHEMBL1727346 | 0.73 | LTA4H (0.42) | DRD2DRD3LMNAALDH1A1LTA4H | |
| SCHEMBL8938994 | 0.73 | LTA4H (0.41) | DRD2DRD4DRD3LTA4HNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |