SCHEMBL757765

SCHEMBL757765

FC(F)(F)C(c1ccc(Oc2ccccc2)cc1)(c1ccc(Oc2ccccc2)cc1)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.52
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
MAOA P21397 1/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
MAPK14 Q16539 1/20 0.43
PDK2 Q15119 2/20 0.42
PDK1 Q15118 1/20 0.42
PDK3 Q15120 1/20 0.42
PDK4 Q16654 1/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
EPHX2 P34913 1/20 0.40
GSTP1 P09211 1/20 0.39
SOS1 Q07889 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21888606 0.92 KIF11 (0.45) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL15308159 0.91 HTT (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL11931987 0.88 SRD5A2 (0.50) LTA4HTSHRMAPK14MEN1KMT2A
SCHEMBL29140665 0.87 MAOA (0.59) TSHRMAOAMEN1KMT2A
SCHEMBL25862493 0.85 ALDH1A1 (0.54) LTA4H
SCHEMBL22590603 0.85 DRD2 (0.42) LTA4HTSHRPDK2PDK1PDK3
SCHEMBL20920725 0.82 ESR2 (0.58) LTA4HNR1H2BAXESR1ESR2
SCHEMBL12360474 0.82 MAPT (0.44) MEN1KMT2A
SCHEMBL21763822 0.82 CETP (0.45) LTA4HMAPK14PDK2PDK1PDK3
SCHEMBL254896 0.82 TSHR (0.59) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820785-B2 Siloxane compound and polyimide precursor composition comprising same LG CHEM, LTD. (KR) 2023-11-21 US disclosed
US-11820785-B2 Siloxane compound and polyimide precursor composition comprising same LG CHEM, LTD. (KR) 2023-11-21 US disclosed
US-11692066-B2 Material for forming organic film, substrate for manufacturing semiconductor device, method for forming organic film, patterning process, and compound for forming organic film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-04 US disclosed
US-20230173798-A1 LAMINATED FILM, AND DISPLAY DEVICE INCLUDING SAME SAMSUNG ELECTRONICS CO LTD (KR) 2023-06-08 US disclosed
US-20220195118-A1 SUBSTRATE FOR HEAT-RESISTANT ELECTRONIC DEVICE LG CHEM, LTD. (KR) 2022-06-23 US disclosed
US-11319409-B2 Polyimide and polyimide film, prepared therefrom, for flexible display LG CHEM, LTD. (KR) 2022-05-03 US disclosed
US-20220033585-A1 DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME LG CHEM, LTD. (KR) 2022-02-03 US disclosed
US-20210317082-A1 DIAMINE COMPOUND, POLYIMIDE PRECURSOR USING SAME, AND POLYIMIDE FILM LG CHEM, LTD. (KR) 2021-10-14 US disclosed
US-11118015-B2 Laminate for manufacturing flexible substrate and method for manufacturing flexible substrate by using same LG CHEM, LTD. (KR) 2021-09-14 US disclosed
US-20210238351-A1 POLYIMIDE PRECURSOR COMPOSITION AND POLYIMIDE FILM, SUBSTRATE FOR DISPLAY DEVICE, AND OPTICAL DEVICE PREPARED BY USING SAME LG CHEM, LTD. (KR) 2021-08-05 US disclosed
US-20120329958-A1 POLYMER SYNTHESIS AND THERMALLY REARRANGED POLYMRES AS GAS SEPARATION MEMBRANES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2012-12-27 US disclosed
US-20120329958-A1 POLYMER SYNTHESIS AND THERMALLY REARRANGED POLYMRES AS GAS SEPARATION MEMBRANES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2012-12-27 US disclosed
US-8138231-B2 Polymer having oxycarbon group, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-20 US disclosed
US-20090233142-A2 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-17 US disclosed
US-20090110995-A1 POLYMER HAVING OXYCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20090048421-A1 FILM FORMING COMPOSITION, FILM, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
US-20090048421-A1 FILM FORMING COMPOSITION, FILM, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-5694513-A Waveguide device and method for production thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
EP-0720030-A1 Waveguide device and method for production thereof HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317082-A1 DIAMINE COMPOUND, POLYIMIDE PRECURSOR USING SAME, AND POLYIMIDE FILM DDC, ODC1, PUF60 LTA4H 4588/4885TSHR 4646/4885NR1H2 4819/4885
US-20220033585-A1 DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME DDC, PUF60, PARG LTA4H 4662/4885TSHR 4095/4885NR1H2 4856/4885
US-11820785-B2 Siloxane compound and polyimide precursor composition comprising same ILK, SMCHD1, PTK2 LTA4H 1059/4885TSHR 4786/4885NR1H2 4385/4885
US-11319409-B2 Polyimide and polyimide film, prepared therefrom, for flexible display WASF2, THEM6, TIAM1 LTA4H 4383/4885TSHR 3641/4885NR1H2 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.