Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942395 | 0.89 | ALOX5 (0.47) | ALOX5LTB4RLTB4R2FFAR1KCNH2 | |
| SCHEMBL8782774 | 0.84 | ALOX5 (0.55) | ALOX5LTB4RLTB4R2FFAR1KCNH2 | |
| SCHEMBL8942302 | 0.82 | ALOX5 (0.41) | ALOX5LTB4RLTB4R2FFAR1BRD4 | |
| SCHEMBL8942484 | 0.82 | PARP10 (0.50) | ALOX5 | |
| SCHEMBL8942653 | 0.79 | CA1 (0.47) | — | |
| SCHEMBL8942623 | 0.78 | HPGD (0.46) | ALOX5 | |
| SCHEMBL8783047 | 0.76 | ALOX5 (0.50) | ALOX5BRD4 | |
| SCHEMBL8942585 | 0.75 | MEN1 (0.42) | ALOX5L3MBTL1 | |
| SCHEMBL8942432 | 0.75 | RAB9A (0.46) | — | |
| SCHEMBL8783028 | 0.73 | ALOX5 (0.53) | ALOX5LTB4RLTB4R2FFAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |