Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942318 | 0.89 | ALOX5 (0.52) | ALOX5LTB4RLTB4R2KCNH2FFAR1 | |
| SCHEMBL8942585 | 0.88 | MEN1 (0.42) | ALOX5ALDH1A1EPHX2 | |
| SCHEMBL8783047 | 0.85 | ALOX5 (0.50) | ALOX5ALDH1A1GPR139EPHX2 | |
| SCHEMBL8942753 | 0.83 | PARP1 (0.52) | ALDH1A1 | |
| SCHEMBL8942302 | 0.80 | ALOX5 (0.41) | ALOX5ALDH1A1LTB4RLTB4R2FFAR1 | |
| SCHEMBL8942429 | 0.78 | PARP10 (0.45) | ALDH1A1 | |
| SCHEMBL8942465 | 0.78 | L3MBTL1 (0.49) | ALDH1A1 | |
| SCHEMBL8942260 | 0.77 | FURIN (0.39) | ALDH1A1 | |
| SCHEMBL8942402 | 0.76 | EPOR (0.46) | ALOX5 | |
| SCHEMBL8942408 | 0.76 | TNKS (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |