Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942817 | 0.89 | GAA (0.42) | PKMHTR6NAMPTLOXMEN1 | |
| SCHEMBL8782842 | 0.84 | PKM (0.54) | PKMHTR2AHTR2CNAMPTLOX | |
| SCHEMBL29280967 | 0.75 | HTR2A (0.68) | HTR2AHTR2CALDH1A1CXCR2LMNA | |
| SCHEMBL8942465 | 0.73 | L3MBTL1 (0.49) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8783392 | 0.73 | MEN1 (0.47) | PKMNAMPTLOXALDH1A1MAPK1 | |
| SCHEMBL8942753 | 0.72 | PARP1 (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL999837 | 0.71 | CXCR2 (0.57) | HTR2AHTR2CALDH1A1CXCR2 | |
| SCHEMBL8942585 | 0.70 | MEN1 (0.42) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29280971 | 0.68 | HDAC6 (0.49) | PKMHTR6NAMPTALDH1A1MEN1 | |
| SCHEMBL8942429 | 0.67 | PARP10 (0.45) | ALDH1A1MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |