Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | NEK4 | P51957 | 3/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.40 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945932 | 0.88 | ITGB3 (0.39) | LMNAHTTSMN1; SMN2EPHX2 | |
| SCHEMBL8945850 | 0.83 | ALDH1A1 (0.43) | LMNAOPRK1 | |
| SCHEMBL8945890 | 0.81 | ALOX5 (0.37) | RPS6KB1OPRK1RIPK1 | |
| SCHEMBL8945911 | 0.81 | ALOX5 (0.36) | LMNASMN1; SMN2OPRK1 | |
| SCHEMBL8945937 | 0.80 | ALOX5 (0.36) | RPS6KB1LMNASMN1; SMN2OPRK1RIPK1 | |
| Hydrochloric Acid SCHEMBL8946104 | 0.78 | ALOX5 (0.34) | RPS6KB1LMNASMN1; SMN2OPRK1RIPK1 | |
| SCHEMBL8945873 | 0.76 | ALOX5 (0.37) | OPRK1 | |
| SCHEMBL27574175 | 0.68 | KMT2A (0.41) | MAPK1LMNASMN1; SMN2MMP9RIPK1 | |
| SCHEMBL8945990 | 0.68 | ALOX5 (0.36) | RIPK1 | |
| SCHEMBL8945821 | 0.68 | KMT2A (0.51) | ROCK1GSK3BCLK4ROCK2RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |