Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8946104 | 0.98 | ALOX5 (0.34) | ALOX5OPRK1RIPK1ALDH1A1HTR1D | |
| SCHEMBL8945911 | 0.82 | ALOX5 (0.36) | ALOX5OPRK1ALDH1A1LMNATP53 | |
| SCHEMBL8945826 | 0.80 | ROCK1 (0.40) | OPRK1RIPK1LMNASMN1; SMN2RPS6KB1 | |
| SCHEMBL8945890 | 0.79 | ALOX5 (0.37) | ALOX5OPRK1RIPK1ALDH1A1MAPT | |
| SCHEMBL8945873 | 0.78 | ALOX5 (0.37) | ALOX5OPRK1 | |
| SCHEMBL8945850 | 0.75 | ALDH1A1 (0.43) | OPRK1ALDH1A1LMNARAB9A | |
| SCHEMBL8945932 | 0.75 | ITGB3 (0.39) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8945990 | 0.70 | ALOX5 (0.36) | ALOX5RIPK1 | |
| SCHEMBL8945931 | 0.68 | MEN1 (0.49) | ALOX5RIPK1ALDH1A1TP53NPC1 | |
| SCHEMBL8946099 | 0.68 | ALOX5 (0.34) | ALOX5RIPK1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |