Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945937 | 0.82 | ALOX5 (0.36) | ALOX5OPRK1MAPTTP53NPC1 | |
| SCHEMBL8945890 | 0.82 | ALOX5 (0.37) | ALOX5OPRK1MAPTNR3C1ALDH1A1 | |
| SCHEMBL8945873 | 0.81 | ALOX5 (0.37) | ALOX5OPRK1NR3C1 | |
| SCHEMBL8945826 | 0.81 | ROCK1 (0.40) | OPRK1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8946104 | 0.81 | ALOX5 (0.34) | ALOX5OPRK1MAPTTP53NPC1 | |
| SCHEMBL8945932 | 0.76 | ITGB3 (0.39) | LMNAALDH1A1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8945850 | 0.76 | ALDH1A1 (0.43) | OPRK1RAB9ANR3C1LMNAPOLB | |
| SCHEMBL8945990 | 0.73 | ALOX5 (0.36) | ALOX5NR3C1 | |
| SCHEMBL8946099 | 0.71 | ALOX5 (0.34) | ALOX5MAPTNR3C1LMNACYP3A4 | |
| SCHEMBL1143876 | 0.70 | ALOX5 (0.41) | ALOX5TP53NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |