Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945826 | 0.88 | ROCK1 (0.40) | HTTEPHX2SMN1; SMN2LMNA | |
| SCHEMBL8945850 | 0.81 | ALDH1A1 (0.43) | KCNA5ALDH1A1LMNACYP2C9CYP2C19 | |
| SCHEMBL8945890 | 0.80 | ALOX5 (0.37) | ALDH1A1 | |
| SCHEMBL8945911 | 0.76 | ALOX5 (0.36) | ALDH1A1SMN1; SMN2LMNACYP2C9CYP2C19 | |
| SCHEMBL8945937 | 0.75 | ALOX5 (0.36) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15591092 | 0.75 | ITGB3 (0.44) | ITGB3ITGAVITGA2BKCNA5HTT | |
| SCHEMBL8945873 | 0.74 | ALOX5 (0.37) | — | |
| SCHEMBL19464263 | 0.74 | TBXAS1 (0.55) | ITGB3ITGAVITGA2BEPHX2TBXAS1 | |
| SCHEMBL6954926 | 0.74 | ITGB3 (0.52) | ITGB3ITGAVITGA2BKCNA5HTT | |
| Hydrochloric Acid SCHEMBL8946104 | 0.74 | ALOX5 (0.34) | ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |