Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946099 | 0.92 | ALOX5 (0.34) | ALOX5NR3C1CXCR1CXCR2OPRD1 | |
| SCHEMBL8945873 | 0.89 | ALOX5 (0.37) | ALOX5NR3C1 | |
| SCHEMBL8945911 | 0.73 | ALOX5 (0.36) | ALOX5NR3C1 | |
| SCHEMBL8945890 | 0.71 | ALOX5 (0.37) | ALOX5NR3C1OPRD1RIPK1 | |
| SCHEMBL8945987 | 0.70 | MEN1 (0.46) | ALOX5CXCR1CXCR2RIPK1 | |
| SCHEMBL8945937 | 0.70 | ALOX5 (0.36) | ALOX5RIPK1 | |
| SCHEMBL8945998 | 0.70 | RIPK1 (0.40) | CXCR1CXCR2OPRD1RIPK1 | |
| SCHEMBL8761523 | 0.69 | SIGMAR1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL9482717 | 0.68 | SIGMAR1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL8946104 | 0.68 | ALOX5 (0.34) | ALOX5RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |