Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946105 | 0.92 | RIPK1 (0.38) | RIPK1MMP8MMP1MMP9MMP13 | |
| SCHEMBL8945878 | 0.89 | RIPK1 (0.39) | RIPK1MMP8MMP1MMP9MMP13 | |
| SCHEMBL8761523 | 0.74 | SIGMAR1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL9482717 | 0.73 | SIGMAR1 (0.46) | — | |
| SCHEMBL8945920 | 0.73 | MMP1 (0.42) | RIPK1MMP8MMP1MMP9MMP13 | |
| SCHEMBL8945987 | 0.70 | MEN1 (0.46) | RIPK1CXCR1CXCR2 | |
| SCHEMBL8945899 | 0.70 | OPRK1 (0.41) | RIPK1MMP8MMP1MMP9MMP13 | |
| SCHEMBL8945805 | 0.70 | MMP8 (0.38) | RIPK1MMP8MMP1MMP9MMP13 | |
| SCHEMBL8945941 | 0.70 | RIPK1 (0.39) | RIPK1MMP8OPRM1OPRD1OPRK1 | |
| SCHEMBL8945990 | 0.70 | ALOX5 (0.36) | RIPK1OPRD1CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |