Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945990 | 0.92 | ALOX5 (0.36) | ALOX5CXCR1CXCR2NR3C1OPRD1 | |
| SCHEMBL8945873 | 0.87 | ALOX5 (0.37) | ALOX5NR3C1 | |
| SCHEMBL8946098 | 0.72 | MEN1 (0.44) | ALOX5CXCR1CXCR2PGRSCN1A | |
| SCHEMBL8945911 | 0.71 | ALOX5 (0.36) | ALOX5NR3C1LMNAMAPTCYP1A2 | |
| SCHEMBL8945890 | 0.70 | ALOX5 (0.37) | ALOX5NR3C1MAPTRPS6KB1ALDH1A1 | |
| SCHEMBL9425081 | 0.69 | PGR (0.40) | CXCR1CXCR2PGRSCN1ASCN2A | |
| SCHEMBL8945937 | 0.68 | ALOX5 (0.36) | ALOX5LMNAMAPTRPS6KB1ALDH1A1 | |
| SCHEMBL9424902 | 0.67 | SIGMAR1 (0.33) | ALOX5CXCR1CXCR2PGRSCN1A | |
| Hydrochloric Acid SCHEMBL8946104 | 0.67 | ALOX5 (0.34) | ALOX5LMNAMAPTRPS6KB1ALDH1A1 | |
| SCHEMBL8945826 | 0.66 | ROCK1 (0.40) | LMNAGAARPS6KB1SMN1; SMN2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |