Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030121 | 0.76 | HTR2B (0.46) | POLBLMNASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL25584892 | 0.76 | NISCH (0.44) | POLBLMNASMN1; SMN2ALDH1A1NISCH | |
| SCHEMBL11559376 | 0.76 | ALDH1A1 (0.44) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21664002 | 0.76 | NISCH (0.44) | POLBLMNASMN1; SMN2ALDH1A1NISCH | |
| SCHEMBL27701214 | 0.71 | ALDH1A1 (0.38) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1147751 | 0.70 | LMNA (0.53) | POLBLMNASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL27985018 | 0.69 | MAOA (0.40) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL505214 | 0.67 | NOS3 (0.50) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28208442 | 0.67 | LMNA (0.37) | POLBLMNASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL28131909 | 0.67 | POLB (0.34) | POLBLMNASMN1; SMN2ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765859-B2 | Polymer-filler coupling additives | BRIDGESTONE CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8765859-B2 | Polymer-filler coupling additives | BRIDGESTONE CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8765859-B2 | Polymer-filler coupling additives | BRIDGESTONE CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-1803713-B1 | Polymer-filler coupling additives | BRIDGESTONE CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-20120083562-A1 | Polymer-Filler Coupling Additives | BRIDGESTONE CORPORATION (JP) | 2012-04-05 | — | — | US | disclosed |
| US-20120083562-A1 | Polymer-Filler Coupling Additives | BRIDGESTONE CORPORATION (JP) | 2012-04-05 | — | — | US | disclosed |
| US-20120083562-A1 | Polymer-Filler Coupling Additives | BRIDGESTONE CORPORATION (JP) | 2012-04-05 | — | — | US | disclosed |
| US-8080605-B2 | Polymer-filler coupling additives | BRIDGESTONE CORPORATION (JP) | 2011-12-20 | — | — | US | disclosed |
| US-8080605-B2 | Polymer-filler coupling additives | BRIDGESTONE CORPORATION (JP) | 2011-12-20 | — | — | US | disclosed |
| US-8080605-B2 | Polymer-filler coupling additives | BRIDGESTONE CORPORATION (JP) | 2011-12-20 | — | — | US | disclosed |
| US-20070161756-A1 | Polymer-Filler Coupling Additives | BRIDGESTONE CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161756-A1 | Polymer-Filler Coupling Additives | BRIDGESTONE CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |
| EP-1803713-A2 | Polymer-filler coupling additives | Bridgestone Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083562-A1 | Polymer-Filler Coupling Additives | BRIX1, PRDX2, PRDX4 | POLB 277/4885LMNA 1081/4885SMN1; SMN2 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.