Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953659 | 0.87 | SIRT2 (0.38) | KMT2ATSHRCCR2LMNASMN1; SMN2 | |
| SCHEMBL8953811 | 0.82 | ALOX5 (0.40) | KMT2ATSHRCCR2LMNASMN1; SMN2 | |
| SCHEMBL9250218 | 0.77 | ALOX5 (0.42) | — | |
| SCHEMBL8953842 | 0.72 | ALOX5 (0.35) | SMN1; SMN2PTGDR2TP53 | |
| SCHEMBL8953863 | 0.72 | ALDH1A1 (0.45) | KMT2ATSHRLMNAHPGD | |
| SCHEMBL8953605 | 0.69 | SIRT2 (0.37) | KMT2ACCR2LMNASMN1; SMN2MAPT | |
| SCHEMBL9254585 | 0.67 | ALOX5 (0.42) | TSHRMAPT | |
| SCHEMBL8953563 | 0.64 | MGLL (0.50) | LMNASMN1; SMN2HTR1F | |
| SCHEMBL20522128 | 0.64 | HCAR1 (0.44) | LMNASMN1; SMN2HTR1F | |
| SCHEMBL8953782 | 0.64 | MAOB (0.40) | KMT2ASMN1; SMN2HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |