Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.35 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690889 | 1.00 | CA1 (0.35) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Potassium Ion SCHEMBL11742623 | 0.98 | CA1 (0.34) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Potassium Ion SCHEMBL11743473 | 0.98 | CA1 (0.34) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Potassium Ion SCHEMBL11544049 | 0.96 | CA1 (0.32) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL11393564 | 0.96 | CA1 (0.32) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Potassium Ion SCHEMBL11542915 | 0.96 | CA1 (0.32) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL94603 | 0.87 | TSHR (0.39) | FOLH1TSHRCTHCBSTHPO | |
| SCHEMBL94605 | 0.82 | LMNA (0.45) | FOLH1TSHRCTHCBSTHPO | |
| SCHEMBL11411214 | 0.82 | FFAR3 (0.33) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL11684412 | 0.81 | CA4 (0.42) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066924-A2 | Detergent powders of improved solubility | UNILEVER N.V. (NL) | 1982-12-15 | — | — | EP | claimed |
| US-4058560-A | TRIALKALI METAL CARBOXYMETHYLOXY SUCCINATE | ETHYL CORPORATION (US) | 1977-11-15 | — | — | US | claimed |
| CN-114829488-A | Polyvinyl alcohol film | 株式会社可乐丽 | 2022-07-29 | — | — | CN | disclosed |
| EP-0299561-B1 | Perfume and bleach compositions | UNILEVER NV (NL) | 1996-01-10 | — | — | EP | disclosed |
| EP-0421327-B1 | Heavy duty laundry detergent | ALBEMARLE CORP (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0217454-B1 | NON-AQUEOUS LIQUID DETERGENT COMPOSITION AND PERBORATE ANHYDROUS | UNILEVER N.V. (NL) | 1992-03-11 | — | — | EP | disclosed |
| EP-0421327-A1 | Heavy duty laundry detergent | ALBEMARLE CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0383482-A2 | Granular automatic dishwasher detergent composition providing glassware protection | THE PROCTER & GAMBLE COMPANY (US) | 1990-08-22 | — | — | EP | disclosed |
| US-4923631-A | MONOPERSULFATE SALTS AND-OR ORGANIC PEROXYACIDS | LEVER BROTHERS COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0299561-A2 | Perfume and bleach compositions | UNILEVER N.V. (NL) | 1989-01-18 | — | — | EP | disclosed |
| US-4772412-A | SODIUM PERBORATE, PEROXY ACID BLEACH PRECURSOR | LEVER BROTHERS COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4379069-A | Detergent powders of improved solubility | LEVER BROTHERS COMPANY (US) | 1983-04-05 | — | — | US | disclosed |
| EP-0066924-A2 | Detergent powders of improved solubility | UNILEVER N.V. (NL) | 1982-12-15 | — | — | EP | disclosed |
| EP-0054436-A1 | Controlled-sudsing detergent compositions | UNILEVER PLC (GB) | 1982-06-23 | — | — | EP | disclosed |
| US-4326979-A | NONIONIC SURFACTANT, SOLVENT, ALKALINE MATERIAL, BUILDER AND HYDROLYZED COPOLYMER OF MALEIC ANHYDRIDE AND ETHYLENE OR METHYL VINYL ETHER; STORAGE STABILITY; | LEVER BROTHERS COMPANY (US) | 1982-04-27 | — | — | US | disclosed |
| EP-0028849-A1 | Non-aqueous, built liquid detergent composition and method for preparing same | UNILEVER N.V. (NL) | 1981-05-20 | — | — | EP | disclosed |
| US-4137260-A | SEEDING WITH TETRAHYDRATE OR PENTAHYDRATE CRYSTALS | ETHYL CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
| US-4100188-A | RECOVERING AN ALKALI METAL, AMMONIUM, OR AMINE SALT OF CARBOXYALKOXY SUCCINIC ACIDS | ETHYL CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |
| US-4071476-A | BIODEGRADABLE | TEXACO INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-4039464-A | ALKALI METAL SALTS OF DIACIDS | TEXACO INC. (US) | 1977-08-02 | — | — | US | disclosed |