Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963855 | 0.89 | TNKS (0.34) | SLC6A2SLC6A4PRMT5TACR1CYP1A2 | |
| SCHEMBL8963505 | 0.87 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3PRMT5TACR1 | |
| SCHEMBL8963527 | 0.86 | PRMT5 (0.32) | PRMT5TNKSPARP1TNKS2DRD2 | |
| SCHEMBL8963580 | 0.85 | PRMT5 (0.40) | SLC6A2SLC6A4PRMT5TACR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.84 | PRMT5 (0.40) | SLC6A2SLC6A4PRMT5TACR1CYP1A2 | |
| SCHEMBL8964088 | 0.83 | OPRD1 (0.37) | PRMT5CYP2D6TNKSPARP1TNKS2 | |
| SCHEMBL8963516 | 0.83 | CHEK2 (0.42) | PRMT5CYP2D6CHEK2ADRB1HTR3A | |
| SCHEMBL8964138 | 0.82 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3PRMT5TACR1 | |
| SCHEMBL8963650 | 0.81 | CHEK2 (0.40) | SLC6A2SLC6A4SLC6A3PRMT5CYP2D6 | |
| SCHEMBL8963675 | 0.80 | TACR1 (0.36) | PRMT5TACR1CYP2C9CYP2C19TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |