Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963855 | 0.89 | TNKS (0.34) | SLC6A2SLC6A4KCNH2CYP2D6TNKS | |
| SCHEMBL8964034 | 0.87 | SLC6A2 (0.36) | SLC6A2SLC6A4CYP2D6TNKSPARP1 | |
| SCHEMBL8963527 | 0.85 | PRMT5 (0.32) | TNKSPARP1TNKS2DRD2DRD3 | |
| SCHEMBL8963580 | 0.84 | PRMT5 (0.40) | SLC6A2SLC6A4TNKSPARP1TNKS2 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.83 | PRMT5 (0.40) | SLC6A2SLC6A4TNKSPARP1TNKS2 | |
| SCHEMBL8964088 | 0.82 | OPRD1 (0.37) | CYP2D6TNKSPARP1TNKS2HTR7 | |
| SCHEMBL8963737 | 0.82 | OPRM1 (0.38) | HTR7HTR3AHTR3EHTR3BADRB1 | |
| SCHEMBL8963532 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4CYP2D6HTR7HTR3A | |
| SCHEMBL8964068 | 0.80 | PRMT5 (0.44) | SLC6A2SLC6A4KCNH2CYP2D6TNKS | |
| SCHEMBL8963637 | 0.80 | MAPK13 (0.37) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |