Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969244 | 0.80 | — | — | |
| SCHEMBL8968684 | 0.74 | ACHE (0.42) | ACHE | |
| SCHEMBL8969499 | 0.70 | CTSD (0.49) | ACHEHRH3 | |
| SCHEMBL8969148 | 0.69 | — | — | |
| SCHEMBL8969087 | 0.68 | AVPR1A (0.33) | HRH3 | |
| SCHEMBL8969504 | 0.68 | ACHE (0.40) | ACHEHRH3HRH1 | |
| SCHEMBL8970324 | 0.68 | MAT2A (0.33) | HRH3 | |
| SCHEMBL8968679 | 0.63 | CTSD (0.47) | ACHEHRH1 | |
| SCHEMBL8969131 | 0.63 | HRH3 (0.31) | HRH3 | |
| SCHEMBL8969833 | 0.62 | ACHE (1.00) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |