Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968401 | 0.75 | OPRM1 (0.34) | OPRM1CTSD | |
| SCHEMBL8970594 | 0.74 | — | — | |
| SCHEMBL8969499 | 0.72 | CTSD (0.49) | CTSDHRH3 | |
| SCHEMBL8969087 | 0.70 | AVPR1A (0.33) | HRH3 | |
| SCHEMBL8969090 | 0.68 | ACHE (0.45) | HRH3 | |
| SCHEMBL8969504 | 0.67 | ACHE (0.40) | CTSDHRH3 | |
| SCHEMBL8968679 | 0.65 | CTSD (0.47) | CTSD | |
| SCHEMBL8968326 | 0.62 | — | — | |
| SCHEMBL8968376 | 0.62 | ACHE (0.44) | DRD3SLC6A3OPRM1CTSD | |
| SCHEMBL8970145 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |