Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 15/20 | 0.63 |
| ▸ | CA1 known ✓ | P00915 | 14/20 | 0.63 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909397 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL11301115 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL6914482 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL6909427 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| Zinc Ion SCHEMBL6915462 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL10547836 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| Potassium Ion SCHEMBL6911291 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL6909054 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL6913292 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 | |
| SCHEMBL6907759 | 0.95 | ALDH1A1 (0.61) | CA2CA1ALDH1A1PLK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108913116-B | Supercritical carbon dioxide reverse-phase association fracturing fluid and preparation method and application thereof | 山东大学 | 2021-04-16 | — | — | CN | claimed |
| EP-0400657-B1 | Process for developing of ps plates requiring no dampening water | FUJI PHOTO FILM CO LTD (JP) | 1996-03-27 | — | — | EP | claimed |
| US-5290665-A | Process for developing PS plate requiring no dampening water wherein the developer comprises, water, a solubilizer and an ethylene glycol mono(alkyl C6 -C8) ether derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| EP-0400657-A2 | Process for developing of ps plates requiring no dampening water | Fuji Photo Film Co., Ltd. (JP) | 1990-12-05 | — | — | EP | claimed |
| CN-108913116-B | Supercritical carbon dioxide reverse-phase association fracturing fluid and preparation method and application thereof | 山东大学 | 2021-04-16 | — | — | CN | disclosed |
| CN-108315000-B | Hydrophobically associating polymer-surfactant composition and binary composite flooding system | 中国石油化工股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| EP-0400657-B1 | Process for developing of ps plates requiring no dampening water | FUJI PHOTO FILM CO LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5290665-A | Process for developing PS plate requiring no dampening water wherein the developer comprises, water, a solubilizer and an ethylene glycol mono(alkyl C6 -C8) ether derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0400657-A2 | Process for developing of ps plates requiring no dampening water | Fuji Photo Film Co., Ltd. (JP) | 1990-12-05 | — | — | EP | disclosed |