Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8992917 | 0.84 | MTNR1A (0.46) | MEN1ALDH1A1LMNAKMT2AFFAR1 | |
| SCHEMBL8992816 | 0.82 | HSD17B10 (0.48) | MEN1ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| Ethylene SCHEMBL6226363 | 0.79 | LMNA (0.48) | ALDH1A1LMNASMN1; SMN2MAPTTYR | |
| Ethylene SCHEMBL10689209 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAKMT2ASMN1; SMN2TACR2 | |
| SCHEMBL10763720 | 0.78 | HSD17B10 (0.57) | ALDH1A1LMNASMN1; SMN2TACR2MAPT | |
| Benzaldehyde SCHEMBL11346796 | 0.75 | ALDH1A1 (0.50) | MEN1ALDH1A1LMNAKMT2APPARG | |
| SCHEMBL11066566 | 0.74 | TBXAS1 (0.52) | ALDH1A1TP53 | |
| Ethylene SCHEMBL8536643 | 0.73 | ALDH1A3 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTTYR | |
| SCHEMBL20546807 | 0.73 | PNMT (0.47) | MEN1ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL30644993 | 0.73 | PNMT (0.47) | MEN1ALDH1A1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |