Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.72 |
| ▸ | CYCS | P99999 | 4/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528996 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL31463072 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL3454784 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL2110994 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL3130597 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL6417052 | 0.97 | CYCS (0.73) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL9273850 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| Zinc Ion SCHEMBL3793018 | 0.97 | TOP1 (0.72) | TOP1CYCSENPP2ABCG2TERT | |
| Hydrochloric Acid SCHEMBL9480288 | 0.95 | TOP1 (0.70) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL11424928 | 0.94 | TOP1 (0.68) | TOP1CYCSENPP2ABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501515-B1 | Optical recording material | TORAY INDUSTRIES (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5306599-A | Optical recording material | TORAY INDUSTRIES, INC. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0501515-A1 | Optical recording material | TORAY INDUSTRIES, INC. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5051337-A | Optical recording material | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1991-09-24 | — | — | US | disclosed |