Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 2/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27303867 | 0.86 | PKLR (0.56) | PKLRAVPR1ACCR3CYP46A1ALDH1A1 | |
| SCHEMBL7804505 | 0.85 | PKLR (0.46) | PKLRCCR3CYP46A1ALDH1A1LMNA | |
| SCHEMBL9011227 | 0.81 | ITGB3 (0.47) | MEN1KMT2ACCR3ALDH1A1LMNA | |
| SCHEMBL7804545 | 0.79 | PKLR (0.47) | PKLRCYP46A1ALDH1A1LMNAPKM | |
| SCHEMBL9011032 | 0.79 | TPSAB1 (0.50) | CCR3CHRM2 | |
| SCHEMBL9010998 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9011197 | 0.76 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL9011281 | 0.75 | NPC1 (0.56) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9011241 | 0.74 | NOS2 (0.53) | ALDH1A1LMNA | |
| SCHEMBL3408619 | 0.70 | AKR1B1 (0.46) | MEN1KMT2AALDH1A1LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |