Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434351 | 0.84 | RAB9A (0.69) | MAPTRAB9AALDH1A1PKMMEN1 | |
| SCHEMBL2853034 | 0.81 | TDP1 (0.66) | MAPTRAB9AALDH1A1PKMMAPK1 | |
| SCHEMBL13752174 | 0.80 | MEN1 (0.53) | MAPTRAB9AALDH1A1HTTMEN1 | |
| SCHEMBL11323600 | 0.79 | PKM (0.77) | MAPTRAB9AALDH1A1PKMMEN1 | |
| SCHEMBL20515482 | 0.79 | TDP1 (0.63) | MAPTRAB9AALDH1A1PKMMAPK1 | |
| SCHEMBL160688 | 0.78 | ESR1 (0.69) | MAPTRAB9AALDH1A1PKMMAPK1 | |
| SCHEMBL3434811 | 0.78 | PKM (0.59) | MAPTRAB9AALDH1A1PKMMAPK1 | |
| SCHEMBL22356355 | 0.78 | THRB (0.66) | MAPTRAB9AALDH1A1HTTMEN1 | |
| SCHEMBL22356462 | 0.78 | THRB (0.66) | MAPTRAB9AALDH1A1HTTMEN1 | |
| SCHEMBL9012180 | 0.78 | MDH1 (0.52) | MAPTRAB9AMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517104-B1 | 1,3,5-Triazine derivatives, their preparation and use as sunscreens | 3V SIGMA SPA (IT) | 1996-11-27 | — | — | EP | claimed |
| US-5233040-A | Light stabilizers for synthetic polymers; sunscreen agents | SIGMA PRODOTTI CHIMICI S.P.A. (IT) | 1993-08-03 | — | — | US | claimed |
| EP-0517104-A1 | 1,3,5-Triazine derivatives, their preparation and use as sunscreens | 3V SIGMA S.p.A (IT) | 1992-12-09 | — | — | EP | claimed |