Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519394 | 0.75 | GPR84 (0.42) | MAPTALDH1A1TDP1L3MBTL1KCNH2 | |
| SCHEMBL9015245 | 0.74 | KCNH2 (0.36) | ALDH1A1KCNH2 | |
| SCHEMBL11041595 | 0.73 | TYMP (0.34) | ALDH1A1KCNH2KDM4EESR1GAA | |
| SCHEMBL1925551 | 0.72 | TYR (0.37) | MAPTTDP1 | |
| SCHEMBL9027341 | 0.71 | ALDH1A1 (0.54) | MAPTALDH1A1TDP1L3MBTL1KCNH2 | |
| SCHEMBL971909 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1TDP1L3MBTL1KCNH2 | |
| SCHEMBL11041473 | 0.70 | HTR1A (0.35) | ALDH1A1KDM4EGAA | |
| SCHEMBL27976370 | 0.70 | TYR (0.40) | MAPTTDP1 | |
| SCHEMBL28490653 | 0.70 | PLK1 (0.46) | MAPTALDH1A1TDP1L3MBTL1KCNH2 | |
| SCHEMBL10879957 | 0.69 | TXNRD1 (0.40) | MAPTALDH1A1TDP1L3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |