Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.48 |
| ▸ | CHRNG | P07510 | 2/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893492 | 0.91 | MMP8 (0.46) | MMP8 | |
| SCHEMBL24001222 | 0.73 | GRIA1 (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8829950 | 0.73 | LMNA (0.49) | — | |
| SCHEMBL14371370 | 0.73 | GRIA1 (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8914296 | 0.72 | DPP7 (0.55) | GRIA1 | |
| SCHEMBL24572013 | 0.71 | MMP2 (0.61) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL26018582 | 0.71 | TRPV1 (0.61) | — | |
| SCHEMBL9436164 | 0.69 | TRPV1 (0.63) | — | |
| SCHEMBL4445755 | 0.69 | CHRNA1 (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL14269025 | 0.68 | LDHA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489425-A | RHODIUM COMPLEXES ATTACHED TO ANTIBODY OR FAB FRAGMENTS FOR THERAPY OR MEDICAL DIAGNOSIS; ANTICARCINOGENIC AND -TUMOR AGENTS; RADIOLOGY; IMMUNOLOGY | THE DOW CHEMICAL COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5284644-A | Anticancer agent; therapy and diagnosis | DOW CHEMICAL COMPANY, THE | 1994-02-08 | — | — | US | disclosed |