Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 9/20 | 0.38 |
| ▸ | NQO1 | P15559 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025049 | 0.82 | G6PD (0.47) | G6PDMAPTHTTNQO2NQO1 | |
| SCHEMBL9023550 | 0.76 | G6PD (0.46) | G6PDMAPTHTTNQO2NQO1 | |
| SCHEMBL9023847 | 0.70 | G6PD (0.39) | G6PDMAPTHTTNQO2NQO1 | |
| SCHEMBL9024129 | 0.68 | ABCB1 (0.36) | G6PDNQO2NQO1ABCB1PARP1 | |
| SCHEMBL9024487 | 0.65 | ABCB1 (0.42) | G6PDNQO2NQO1ABCB1P2RX4 | |
| SCHEMBL9024798 | 0.64 | NQO2 (0.56) | NQO2NQO1MEN1LMNAKMT2A | |
| SCHEMBL9024559 | 0.64 | MAPT (0.39) | G6PDMAPTHTTMEN1RGS12 | |
| SCHEMBL9023936 | 0.62 | NQO2 (0.34) | G6PDMAPTHTTNQO2NQO1 | |
| SCHEMBL9024667 | 0.62 | NQO1 (0.39) | NQO2NQO1MEN1LMNAKMT2A | |
| SCHEMBL9023798 | 0.61 | MAPT (0.41) | MAPTHTTNQO2NQO1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |