Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 10/20 | 0.36 |
| ▸ | PYGM | P11217 | 10/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086984 | 0.86 | PYGL (0.45) | PYGLPYGMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9047294 | 0.80 | ALOX15 (0.40) | PYGLPYGMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9046285 | 0.76 | KMT2A (0.45) | PYGLPYGMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9045462 | 0.70 | SLC6A3 (0.38) | PYGLPYGMLMNAHTTCYP2C9 | |
| SCHEMBL8441926 | 0.70 | TSHR (0.42) | PYGLPYGMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9829022 | 0.70 | PYGL (0.48) | PYGLPYGMALOX15 | |
| SCHEMBL8082470 | 0.69 | ALOX15 (0.51) | PYGLPYGMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10376495 | 0.68 | PYGL (0.44) | PYGLPYGML3MBTL1ALDH1A1POLB | |
| SCHEMBL10374293 | 0.67 | PYGM (0.49) | PYGLPYGM | |
| SCHEMBL9048171 | 0.67 | HSD17B10 (0.49) | ALDH1A1SMN1; SMN2ALOX15KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705830-A1 | 2,3-Cyclic condensed 1,4-dihydropyridines, process for their preparation and their use as K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |